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Postdoctoral Position at the NIH

NIH/NIA

Baltimore, MD

Job posting number: #7075499

Posted: February 25, 2021

Application Deadline: May 26, 2021

Job Description

The National Institute on Aging (NIA), a major research component of the National Institutes of Health (NIH) and the Department of Health and Human Services (DHHS), is recruiting for a postdoctoral position in the Section on DNA Helicases, Translational Gerontology Branch. The focus of our group is to investigate the functions of helicase enzymes defective in hereditary disorders displaying age-associated clinical features and/or cancer. The objective of this research is to understand the molecular and cellular roles of human DNA helicases in pathways that are important for the maintenance of genome integrity and cellular homeostasis. Genetic and biochemical approaches are used to characterize the roles of helicases in cellular nucleic acid metabolism through their catalytic functions and protein interactions. State-of-the art experimental approaches include the use of siRNA/CRISPR screens, pharmacologically active small molecules, single-molecule DNA fiber studies, live cell imaging by immunofluorescence confocal microscopy, protein biochemistry, and enzyme kinetic assays. Molecular therapies are tested in preclinical models for translational approaches. Interested candidates must have a Ph.D. or M.D., with less than five years of postdoctoral experience, research experience in molecular biology, as well as training in mammalian cell culture techniques. Please submit a letter of interest, curriculum vitae, and references to: Robert M. Brosh, Jr., Ph.D., Senior Investigator NIA-NIH, Translational Gerontology Branch, 251 Bayview Blvd., Suite 100, Baltimore, MD 21224 or by email to broshr@mail.nih.gov. For additional information, visit: https://irp.nih.gov/pi/robert-brosh.

Disclaimers: DHHS and NIH are Equal Opportunity Employers. The NIH is dedicated to building a diverse community in its training and employment programs and encourages the application and nomination of qualified women, minorities, and individuals with disabilities.

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