Job DescriptionPosition 1. The Bystroff laboratory @ RPI is developing vaccines for immuno-contraception in women and men, a hypoallergenic COVID vaccine, and a vaccine against metastatic cancer. We design self-assembling, highly immunogenic, multivalent particles expressed in bacteria, yeast and human cells. The contraceptive vaccine will be tested in mice and in a prominent sperm physiology lab at Yale University Medical School. Our team is changing the way vaccines are made delivered and tested, from computational design to animal (mouse and primate) testing. Experience in molecular biology and protein purification is essential. Experience with ultracentrifugation, HPLC, dynamic light scattering and/or transmission electron microscopy is a plus.
Position 2. The Bystroff lab is also developing computationally designed fluorescent biosensors based on green fluorescent protein. This NIH-funded project seeks to expand the leave-one-out strategy for protein design, using the power of split protein reconstitution and computational protein design using GROMACS and MOE. Our collaborators at TAMU are studying the immobilization of our designed biosensors on hyperstable protein fibers. Molecular biology and protein purification skills are essential. Experience with fluorimetry and/or molecular modeling is a plus.
We seek talented researchers for two postdoctoral appointments of 1-3 years with experience in cloning and protein expression in bacteria, yeast and mammalian cells. Candidates must possess a Doctoral Degree in a biology, biochemistry, biotechnology, chemistry or a related discipline and have experience in cloning and protein expression in yeast. Candidates must have a passion for science and biotechnology.
Please apply at https://careers.rpi.edu/en-us/job/492489/biotechnology-and-life-sciences-researchers